发明名称 |
NON-COVALENT COMPLEX COMPRISING AT LEAST AN ANTIBODY AND ELEMENT BINDING WITH IMMUNOGLOBULINS ASSOCIATED WITH AN ACTIVE SUBSTANCE, METHOD OF PREPARING AND APPLICATIONS |
摘要 |
The invention concerns a non-covalent complex comprising at least an antibody or an antibody fragment capable of binding with a molecule expressed at a cell surface and an element binding with immunoglobulins (Igs), associated with an active substance, said complex having a specific affinity for appropriate target cells. The invention also concerns said complexes and their applications. Said non-covalent complex comprises (i) at least an antibody or an antibody fragment capable of being bound with a molecule expressed at a cell surface and (ii) an element binding with immunoglobulins, associated with an active substance, said binding element can only be bound with a single type of site on the immunoglobulin.
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申请公布号 |
WO9834956(A1) |
申请公布日期 |
1998.08.13 |
申请号 |
WO1998FR00227 |
申请日期 |
1998.02.06 |
申请人 |
COMMISSARIAT A L'ENERGIE ATOMIQUE;DREVET, PASCAL;LEONETTI, MICHEL;MENEZ, ANDRE |
发明人 |
DREVET, PASCAL;LEONETTI, MICHEL;MENEZ, ANDRE |
分类号 |
A61K39/38;A61K39/385;A61K47/48;C07K16/00;C07K16/28;C07K16/42;(IPC1-7):C07K16/00 |
主分类号 |
A61K39/38 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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