发明名称 |
Substituted thiophenesulfonylureas and -thioureas, processes for their preparation, their use as a medicament or diagnostic, and medicament containing them |
摘要 |
Substituted thiophenesulfonylureas and -thioureas I <IMAGE> I wherein R(1) is selected from the group consisting of hydrogen, halogen, alkyl having 1 or 2 carbon atoms, alkoxy having 1 or 2 carbon atoms, mercaptoalkyl having 1 or 2 carbon atoms, fluoroalkoxy having 1 or 2 carbon atoms, and fluoroalkyl having 1 or 2 carbon atoms; R(2) is selected from the group consisting of hydrogen, alkyl having 1 or 2 carbon atoms such as methyl, alkoxy having 1 or 2 carbon atoms, and trifluoromethyl; X is selected from the group consisting of oxygen (compounds Ia) or sulfur (compounds Ib); Y and Z are identical or different and are selected from the group consisting of hydrogen, F, Cl, Br, I, alkyl having 1 or 2 carbon atoms and alkoxy having 1 or 2 carbon atoms.
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申请公布号 |
US5792788(A) |
申请公布日期 |
1998.08.11 |
申请号 |
US19960593621 |
申请日期 |
1996.01.30 |
申请人 |
HOECHST AKTIENGESELLSCHAFT |
发明人 |
ENGLERT, HEINRICH;HARTUNG, JENS;CRAUSE, PETER;MANIA, DIETER;GOEGELEIN, HEINZ;KAISER, JOACHIM |
分类号 |
A61K31/38;A61K31/381;A61K31/64;A61P9/00;A61P9/04;A61P9/06;A61P9/10;A61P43/00;C07D333/34;(IPC1-7):A61K31/38;C07D333/32 |
主分类号 |
A61K31/38 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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