发明名称 |
Expandable gastro-retentive therapeutic system with controlled active substance release in the gastro-intestinal tract |
摘要 |
The present invention describes a device for the controlled release of active compounds in the gastrointestinal tract with delayed pyloric passage, having a component expandable on contact with gastric juice, which is surrounded by a polymer covering which is permeable to gastric juice and active compounds. The device contains at least one active compound which is present in a multiparticulate preparation which releases the active compound into the gastric juice with a delay. Compared with conventional pharmaceutical forms with delayed pyloric passage, the release of active compound from a device according to the invention can be better controlled; likewise the device can be easily rolled or folded and can be introduced into capsules without problems. |
申请公布号 |
AU6292298(A) |
申请公布日期 |
1998.08.07 |
申请号 |
AU19980062922 |
申请日期 |
1998.01.09 |
申请人 |
LTS LOHMANN THERAPIE-SYSTEME GMBH |
发明人 |
BODO ASMUSSEN;KARSTEN CREMER;HANS-RAINER HOFFMANN;KARIN LUDWIG;MICHAEL ROREGER |
分类号 |
A61D7/00;A61K9/00;A61K9/48;A61K9/52;A61M31/00 |
主分类号 |
A61D7/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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