| 摘要 |
A fillable dermal or transdermal delivery device that utilizes injection ports for post assembly introduction of medicinally active or inactive agents. The device is comprised of a pressure sensitive skin contact adhesive layer which is affixed to a diffusion membrane comprised of a porous film. A backing layer is provided and is sealed along its perimeter to the perimeter of the porous film, thereby creating a fillable reservoir. The reservoir is filled by means of a loading port that is comprised of a septum. The fillable reservoir is filled by means of a loading needle such as a hypodermic needle that is inserted through the septum of the loading port. A shield is provided in the interior of the fillable reservoir to protect the diffusion membrane from damage in the event that the hypodermic needle is inserted far enough through the loading port to make contact with the porous film. |
