发明名称 Mittel zur Entquellung von Hornhäuten in der Organkultur
摘要 An agent for dehydrating corneas, in particular eye corneas for organ culture, contains the culture medium and as dehydrating substance hydroxyethylstarch with a mean molecular weight MW from 70,000 to 200,000, an MS substitution degree from 0.15 to 0.5, a DS substitution degree from 0.15 to 0.5 and a C2-C6 substitution ratio at the anhydroglucose units >/= 8. The dehydrating substance is preferably hydroxyethylstarch with a mean molecular weight MW 130,000 +/- 20,000, an MS substitution degree from 0.38 to 0.45, a DS substitution degree from 0.32 to 0.40 and a C2-C6 substitution ratio at the anhydroglucose units from 8 to 20. The hydroxyethylstarch is used in a concentration from 1 to 20 (weight/vol.) %, preferably from 2 to 15 (weight/vol.) %, and in particular of 7.5 % (weight/vol.). Also disclosed is the use of this hydroxyethylstarch as a dehydrating substance for the organ culture of corneas, in particular eye corneas, and the use of this hydroxyethylstarch for preparing a dehydrating agent for corneas, in particular eye corneas for organ culture.
申请公布号 DE19702210(A1) 申请公布日期 1998.08.06
申请号 DE19971002210 申请日期 1997.01.23
申请人 FRESENIUS AG, 61350 BAD HOMBURG, DE 发明人 REDBRAKE-ADAMS, CLAUDIA, PRIV. DOZ. DR.MED., 52076 AACHEN, DE;REIM, MARTIN, PROF. DR.MED., 52074 AACHEN, DE
分类号 C12N5/06;A01N1/02;A61L27/00;C08B31/02;C12N5/08;(IPC1-7):A01N1/02 主分类号 C12N5/06
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