发明名称 |
COMPOSITIONS AND METHODS FOR IMAGING GENE EXPRESSION |
摘要 |
Described are short peptide sequences, termed recombinant peptide chelates (RPCs), and the imaging marker genes that encode them. The RPCs can be expressed in parallel with the expression of any other desired gene (e.g., a therapeutic gene), and used to easily confirm the expression of the therapeutic gene product. The RPCs are expressed in the cell or on the cell surface concurrently with the therapeutic gene product, and can be assayed by standard imaging techniques.
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申请公布号 |
WO9833809(A1) |
申请公布日期 |
1998.08.06 |
申请号 |
WO1998US01768 |
申请日期 |
1998.01.30 |
申请人 |
THE GENERAL HOSPITAL CORPORATION |
发明人 |
BOGDANOV, ALEXEI, A.;WEISSLEDER, RALPH;SIMONOVA, MARIA |
分类号 |
C07K7/08;(IPC1-7):C07K2/00;C12N15/63 |
主分类号 |
C07K7/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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