PEPTIDES WITH ORGANO-PROTECTIVE ACTIVITY, THERAPEUTIC AGENT CONTAINING THESE PEPTIDES AND THEIR USE

摘要

Synthetic peptides containing from 8 to 15 amino acid residuals of common formula Xaa Zaa Pro Pro Pro Xaa Yaa Pro Ala Asp Zaa Ala Xaa, Xaa Xaa, in which Xaa is a neutral residual of aliphatic acid like Ala, bAla, Leu, Ile, Gly, Val, Nle, Nva, Yaa is a basic residual of amino acid like Lys, Arg, Orn, His and Zaa is an acid residual of amino acid like Glu, Asp, Aad or Apm, whilst at least one of the Xaa or Zaa residuals might be omitted. Described peptides perform a similar biological activity as the natural compound BPC.