发明名称 |
Antibody which is directed against and inhibits collagen binding to a VLA-1 epitope and uses thereof |
摘要 |
The present invention provides methods of treating a subject suffering from a disorder associated with elevated levels of VLA-1 which comprises administering to the subject a therapeutically effective amount of an antibody which specifically forms a complex with VLA-1, inhibits collagen binding to VLA-1, and is directed to the epitope to which antibody 1B3.1 (ATCC No. HB10536) is directed and a pharmaceutically acceptable carrier.
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申请公布号 |
US5788966(A) |
申请公布日期 |
1998.08.04 |
申请号 |
US19950390528 |
申请日期 |
1995.02.17 |
申请人 |
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK |
发明人 |
CHESS, LEONARD;BANK, ILAN |
分类号 |
C07K16/28;G01N33/569;(IPC1-7):A61K39/395 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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