摘要 |
The invention is directed to the sterilization of bone tissue for transplantation employing a hydrogen peroxide vapor sterilant. The bone tissue is exposed to the sterilant vapor at a pressure, temperature, and concentration, and for a period of time that is sufficient to sterilize the bone tissue, but insufficient to cause substantial physical, chemical and biological damage. The bone tissue is defatted, preferably demineralized, substantially free of moisture and blood, and may be lyophilized prior to sterilization.
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