Method of treating depression with certain triazine derivatives

摘要

PCT No. PCT/JP94/01455 Sec. 371 Date Apr. 25, 1995 Sec. 102(e) Date Apr. 25, 1995 PCT Filed Sep. 2, 1994 PCT Pub. No. WO95/07282 PCT Pub. Date Mar. 16, 1995The present invention relates to an antidepressant containing as an active ingredient a triazine derivative or a pharmaceutically acceptable salt thereof, the derivative being represented by the following Formula (I): <IMAGE> (I) in which, R1 represents hydrogen, substituted or unsubstituted lower alkyl, or substituted or unsubstituted lower alkanoyl; R2 represents hydrogen, substituted or unsubstituted lower alkyl, substituted or unsubstituted lower alkenyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted aryl, substituted or unsubstituted aralkyl, or a substituted or unsubstituted heterocyclic group; R3 represents a substituted or unsubstituted heterocyclic group; X represents a single bond, O, S, S(O), S(O)2, or NR4 (in which R4 represents hydrogen, or substituted or unsubstituted lower alkyl; or R2 and NR4 are combined to form a substituted or unsubstituted 4 to 6-membered saturated heterocyclic group); and A represents N or CR5 (in which R5 represents hydrogen, or substituted or unsubstituted lower alkyl).