| 摘要 |
A process for producing an alkoxycarbonylaminothiazoleacetic acid derivative, which comprises reacting an aminothiazoleacetic acid derivative ester with a dialkyl dicarbonate in the presence of a dialkyl carbonate to form an alkoxycarbonylaminothiazoleacetic acid derivative ester, then hydrolyzing the ester with a base, separating the carbonate formed as a by-product, and neutralizing the remaining base. The process can produce an alkoxycarbonylaminothiazoleacetic acid derivative in a simple operation and safely, at a high yield and at a high reactor yield.
|
