发明名称 |
Protein prenyltransferase |
摘要 |
The present invention relates, in general, to a protein prenyltransferase and, in particular, to protein geranylgeranyltransferase (GGTase-I) and to a nucleic acid sequence encoding same. The invention also relates to methods of producing GGTase-I and geranylgeranyl modified polypeptides. The invention further relates to a method of screening compounds for the ability to alter GGTase-I activity.
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申请公布号 |
US5789558(A) |
申请公布日期 |
1998.08.04 |
申请号 |
US19940188277 |
申请日期 |
1994.01.31 |
申请人 |
MERCK & CO., INC.;DUKE UNIVERSITY |
发明人 |
CASEY, PATRICK J.;ZHANG, FANG;DIEHL, RONALD E.;KOHL, NANCY E.;OMER, CHARLES A. |
分类号 |
C12N15/09;C12N5/10;C12N9/10;C12N9/99;C12N15/54;C12Q1/48;C12R1/91;(IPC1-7):C12N9/10 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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