| 发明名称 |
System for assaying binding to a heparin-binding growth factor receptor |
| 摘要 |
A homogeneous population of cells having on average (1) a number of cell surface low-affinity heparin-binding growth factor (HBGF) sites per cell less than 20% of the number of such binding sites found on wild-type CHO-K1 cells (ATCC Accession No. CCL61), and at least three times the number of cell surface high-affinity HBGF receptors per cell found on such CHO-K1 cells; and an assay system utilizing such cells.
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| 申请公布号 |
US5789182(A) |
申请公布日期 |
1998.08.04 |
| 申请号 |
US19930166717 |
申请日期 |
1993.12.14 |
| 申请人 |
THE CHILDREN'S MEDICAL CENTER CORPORATION;PRESIDENT AND FELLOWS OF HARVARD COLLEGE |
发明人 |
YAYON, AVNER;ORNITZ, DAVID M.;KLAGSBRUN, MICHAEL;LEDER, PHILIP;FLANAGAN, JOHN G. |
| 分类号 |
C07K14/50;C07K14/71;C12N9/16;G01N33/50;G01N33/74;(IPC1-7):C12Q1/00;C12N15/09 |
主分类号 |
C07K14/50 |
| 代理机构 |
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