发明名称 |
Recombinant human iga-j. chain dimer |
摘要 |
Disclosed are compositions and methods of use that comprise engineered IgA antibodies that, when administered to a host are secreted across the epithelium into the mucosal barriers of the body providing external passive immunotherapy against agents such as viral, bacterial and eukaryotic pathogens. Also disclosed are mini antibodies comprising the minimal transcytosis domains. |
申请公布号 |
AU5915498(A) |
申请公布日期 |
1998.08.03 |
申请号 |
AU19980059154 |
申请日期 |
1998.01.07 |
申请人 |
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
J. DONALD CAPRA;JONATHAN M. HEXHAM;LEON N. CARAYANNOPOULOS;EDWARD E MAX |
分类号 |
A61K38/00;C07K16/00;C07K16/10;C07K16/44;C12P21/08 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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