发明名称 Methods and compositions for inhibiting cell proliferative disorders
摘要 The present invention concerns compounds and their use to inhibit the activity of a receptor tyrosine kinase. The invention is preferably used to treat cell proliferative disorders such as cancers characterized by over-activity or inappropriate activity HER2 or EGFR.
申请公布号 US5789427(A) 申请公布日期 1998.08.04
申请号 US19950399967 申请日期 1995.03.07
申请人 SUGEN, INC.;YISSUM RESEARCH & DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM 发明人 CHEN, HUI;GAZIT, AVIV;HIRTH, KLAUS PETER;MANN, ELAINA;SHAWVER, LAURA K.;TSAI, JIANMING;TANG, PENG CHO
分类号 A61K31/245;A61K31/277;A61K31/415;A61K31/4184;A61K31/4402;A61K31/498;A61K31/517;C07C229/60;C07C255/36;C07C255/37;C07C255/41;C07C255/42;C07C255/66;C07C311/27;C07C317/46;C07C327/44;C07D241/52;(IPC1-7):A01N43/40;C07D211/72 主分类号 A61K31/245
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