摘要 |
1,238,280. Insolubilized enzymes. MUANYAGIPARI KUTATO INTEZET. 31 Oct., 1969 [6 Nov., 19681, No. 53588/69. Headings C3H and C3P. In a process for the production of waterinsoluble enzyme and antigen preparations having high activity and stability, one or more water-soluble monomers are added to an aqueous solution of the enzyme or antigen, at least one of the monomers being able to cross-link during polymerization, and the system is then subjected to X-ray or gamma-ray radiation of 300 to 30,000 rad./hour intensity until at least 80% of the monomers become polymerized. In examples, trypsin is added to an aqueous solution of acrylamide and bisacrylamide which is then irradiated with X-rays in an argon atmosphere. A porous material such as porous polyvinyl chloride, porous polystyrene, urea-formaldehyde resin foam, polyvinyl alcohol foam, porous felt or cotton wool may be added to the mixture before polymerization. |