| 摘要 |
1,195,639. Pyrazine derivatives. DAIICHI SEIYAKU CO. Ltd. 19 Sept., 1968 [20 Sept., 1967 (2)], No. 44627/68. Heading C2C. Novel compounds (I) in which X is C 1-5 alkoxy, piperidino, morpholino or oxazolidino and Y is H or C 1-5 alkoxy are prepared by reacting the appropriate Y-substituted pyrazine-2-carboxylic acid with a C 1-5 alkanol and where required reacting the resulting ester with piperidine, morpholine or oxazolidine. Intermediates isolated are 6-chloro-pyrazine-2- carboxylic acid, prepared by reacting pyrazine-2- carboxylic acid-4-oxide with phosphoryl chloride and 6-methoxy-pyrazine-2-carboxylic acid, prepared by reacting the former-named intermediate with sodium methoxide.
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