发明名称 PYRAZOLOPYRIMIDINONES FOR THE TREATMENT OF IMPOTENCE
摘要 <p>The use of a compound of formula (I) wherein R1 is H; C1-C3 alkyl; C1-C3 perfluomalkyl; or C3-C5 cycloalkyl; R2 is H; optionally substituted C1-C6 alkyl; C1-C3 pefluoroalkyl; or C3-C6 cycloalkyl; R3 is optionally substituted C1-C6 alkyl; C1-C6 perfluoroalkyl; C3-C5 cycloalkyl; C3-C6 alkenyl; or C3-C6 alkynyl; R4 is optionally substituted C1-C4 alkyl, C2-C4 alkenyl, C2-C4 alkanoyl, (hydroxy)C2-C4 alkyl or (C2-C3 alkoxy)C1-C2 alkyl; CONR5R6; CO2R7; halo; NR5R6; NHSO2NR5R6; NHSO2R8; SO2NR9R10; or phenyl, pyridyl, pyrimidinyl, imidazolyl, oxazolyl, thiazolyl, thienyl or triazolyl any of which is optionally substituted with methyl; R5 and R6 are each independently H or C1-C4 alkyl, or together with the nitrogen atom to which they are attached form an optionally substituted pyrrolidinyl, piperidino, morpholino, 4-N(R11)-piperazinyl or imidazolyl group; R7 is H or C1-C4 alkyl; R8 is optionally substituted C1-C3 alkyl; R9 and R10 together with the nitrogen atom to which they are attached form an optionally su</p>
申请公布号 GR3026520(T3) 申请公布日期 1998.07.31
申请号 GR19980400704T 申请日期 1998.04.03
申请人 PFIZER LIMITED;PFIZER RESEARCH AND DEVELOPMENT COMPANY, N.V./S.A. 发明人 ELLIS, PETER;TERRETT, NICHOLAS KENNETH
分类号 A61K45/00;A61K;A61K31/00;A61K31/505;A61K31/519;A61K31/522;A61K31/529;A61K31/535;A61P13/02;A61P15/00;A61P15/10;C07D487/04;(IPC1-7):A61K31/505 主分类号 A61K45/00
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