发明名称 |
Angiotensin II receptor blocking 2,3,6-substituted quinazolones |
摘要 |
<p>Novel quinazolinone compounds of the formula: <CHEM> wherein R<5>, R<6>, R<7>, R<8>, R and X are defined in the specification, which have angiotensin II (AII) antagonizing activity, intermediates useful in the preparation of the compounds, methods of producing and using the compounds to alleviate angiotensin induced hypertension and treat congestive heart failure in mammals.</p> |
申请公布号 |
GR3026592(T3) |
申请公布日期 |
1998.07.31 |
申请号 |
GR19980400781T |
申请日期 |
1998.04.10 |
申请人 |
AMERICAN CYANAMID COMPANY |
发明人 |
VENKATESAN, ARANAPAKAM M.;LEVIN, JEREMY I. |
分类号 |
A61K31/505;A61K31/517;A61P9/00;A61P9/12;A61P43/00;C07D239/88;C07D239/90;C07D239/91;C07D257/04;C07D403/10;C07F7/08;C07F7/18;(IPC1-7):C07D403/10;A61K31/455 |
主分类号 |
A61K31/505 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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