Process for producing D-alpha-amino acids

摘要

The invention relates to a gene which pertains to D-N-carbamoyl- alpha -amino acid amidohydrolase which converts D-N-carbamoyl- alpha -amino acid into D- alpha -amino acid; a recombinant plasmid comprising a DNA fragment containing the gene integrated into a vector; a microorganism belonging to the genus Escherichia, Pseudomonas, Flavobacterium, Bacillus, Serratia, Corynebacterium or Brevibacterium and transformed by integrating the recombinant plasmid therein; a process for producing D-N-carba-moyl- alpha -amino acid amidohydrolase by culturing the transformed microorganism; D-N-carbamoyl- alpha -amino acid amidohydrolase produced thereby; and a process for producing D- alpha -amino acid by the action of the amidohydrolase. The amidohydrolase can be used also in a state immobilized on a carrier.