发明名称 |
lep |
摘要 |
lep polypeptides and DNA (RNA) encoding such lep and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such lep for the treatment of infection, particularly bacterial infections. Antagonists against such lep and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of lep nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding leader peptidase and for detecting the polypeptide in a host.
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申请公布号 |
US5786197(A) |
申请公布日期 |
1998.07.28 |
申请号 |
US19960756299 |
申请日期 |
1996.11.25 |
申请人 |
SMITHKLINE BEECHAM CORPORATION |
发明人 |
LONETTO, MICHAEL ARTHUR |
分类号 |
G01N33/50;A61K31/70;A61K35/76;A61K38/00;A61K38/46;A61K38/48;A61K39/00;A61K39/09;A61K39/395;A61K48/00;A61P9/00;A61P11/00;A61P27/02;A61P27/16;A61P29/00;A61P31/04;A61P31/10;A61P43/00;C07K14/315;C07K16/40;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/52;C12N15/00;C12N15/09;C12N15/57;C12P21/08;C12Q1/00;C12Q1/02;C12Q1/68;C12R1/19;C12R1/46;G01N33/15;G01N33/53;G01N33/566;G01N33/573;(IPC1-7):C12N9/52;C12N9/50;C12N1/20;C07H21/04 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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