发明名称 |
Human phospholipase activating protein and methods for diagnosis of rheumatoid arthritis |
摘要 |
The invention provides methods for detecting elevated levels of phospholipase A2 activating protein in persons suspected of having rheumatoid arthritis to thereby indicate the presence of rheumatoid arthritis in the person comprising the steps of providing a sample of body fluid or tissue from said person; contacting the sample with an antibody specific for phospholipase A2 activating protein such that the antibody binds with phospholipase A2 activating protein in the sample; detecting the antibody thereby indicating the presence of phospholipase A2 activating protein, whereby elevated levels of phospholipase A2 activating protein in the sample as compared with levels found in persons not having rheumatoid arthritis indicates the presence of rheumatoid arthritis in the person. Kits and reagents for detecting rheumatoid arthritis are also provided.
|
申请公布号 |
US5786154(A) |
申请公布日期 |
1998.07.28 |
申请号 |
US19950465421 |
申请日期 |
1995.06.05 |
申请人 |
BOMALASKI, JOHN S.;CLARK, MIKE A.;SHORR, ROBERT |
发明人 |
BOMALASKI, JOHN S.;CLARK, MIKE A.;SHORR, ROBERT |
分类号 |
C07K14/00;A61K38/00;C07K1/16;C07K14/47;C07K16/00;C07K16/18;C12N15/113;C12N15/55;G01N33/53;G01N33/564;(IPC1-7):G01N33/543;G01N33/573 |
主分类号 |
C07K14/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|