发明名称 |
Method of preventing formation of adhesions following surgery |
摘要 |
Collagen-based compositions useful in the attachment of tissues, or the attachment of tissues to synthetic implant materials, are disclosed. The compositions comprise collagen crosslinked using a multifunctionally activated synthetic hydrophilic polymer. A particularly preferred composition comprises fibrillar collagen, a fiber disassembly agent, and a multifunctionally activated synthetic hydrophilic polymer. Methods are disclosed for using the compositions to effect the attachment of a native tissue to the surface of another native tissue, a non-native tissue, or a synthetic implant. Also disclosed are methods of using the compositions to prevent the formation of surgical adhesions.
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申请公布号 |
US5786421(A) |
申请公布日期 |
1998.07.28 |
申请号 |
US19970853045 |
申请日期 |
1997.05.06 |
申请人 |
COHESION TECHNOLOGIES, INC. |
发明人 |
RHEE, WOONZA M.;RAO, PREMA R.;CHU, GEORGE H.;DELUSTRO, FRANK A.;HARNER, CAROL F. H.;SAKAI, NAOMI;SCHROEDER, JACQUELINE A. |
分类号 |
A61L24/00;A61F2/00;A61F2/06;A61K38/00;A61K47/48;A61L24/10;A61L26/00;A61L27/18;A61L27/20;A61L27/24;A61L27/26;A61L27/34;A61L27/44;A61L27/54;A61L29/04;A61L29/06;A61L29/16;A61L31/04;A61L31/10;A61L31/12;C07K14/495;C07K14/78;C08B37/08;C08H1/06;C08L89/06;C09J189/06;(IPC1-7):A61F13/00;A61B17/07 |
主分类号 |
A61L24/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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