| 发明名称 |
Therapeutic and diagnostic methods and compositions based on notch proteins and nucleic acids |
| 摘要 |
The present invention relates to diagnostic methods and compositions for detection of malignancy or nervous system disorders based on the level of Notch proteins or nucleic acids. Therapeutic methods and methods of inhibiting Notch expression are also provided.
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| 申请公布号 |
US5786158(A) |
申请公布日期 |
1998.07.28 |
| 申请号 |
US19930083590 |
申请日期 |
1993.06.25 |
| 申请人 |
YALE UNIVERSITY |
发明人 |
ARTAVANIS-TSAKONAS, SPYRIDON;FEHON, RICHARD GRANT;ZAGOURAS, PANAYIOTIS;BLAUMUELLER, CHRISTINE MARIE |
| 分类号 |
G01N33/53;A01N37/18;A61K31/70;A61K38/00;A61K38/17;A61K39/395;A61K48/00;A61P1/16;A61P17/00;A61P25/00;A61P35/00;A61P43/00;C07H21/04;C07K14/435;C07K14/47;C07K14/705;C12N1/21;C12N15/09;C12N15/62;C12P21/02;C12R1/19;G01N33/574;G01N33/68;(IPC1-7):G01N33/574 |
主分类号 |
G01N33/53 |
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