发明名称 |
Metal chelate forming peptides and use thereof represented by three amino acid sequences |
摘要 |
The invention provides, inter alia, metal radionuclide-labelled reagent comprising a metal radionuclide coordinated with a metal chelate forming peptide having an amino acid sequence of three amino acid residues represented by: X1-X2-Cys, wherein X1 represents an Asp residue, a Tyr residue or a Lys residue; X2 represents an amino acid residue other than a Cys residue and a Pro residue, provided that X2 does not represent a Gly residue when X1 represents an Asp residue; wherein functional groups at the N-terminus, C-terminus and side chain may be optionally substituted with protecting groups; and wherein each of the amino acid residues may be either D-form or L-form.
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申请公布号 |
US5785948(A) |
申请公布日期 |
1998.07.28 |
申请号 |
US19970815530 |
申请日期 |
1997.03.12 |
申请人 |
NIHON MEDI-PHYSICS CO., LTD. |
发明人 |
ITAYA, YOSHITOSHI;SEKI, IKUYA;HANAOKA, KOICHI;SHIRAKAMI, YOSHIFUMI |
分类号 |
A61K51/08;C07K5/087;C07K5/09;C07K5/093;C07K7/08;(IPC1-7):A61K51/00;A61M36/14 |
主分类号 |
A61K51/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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