Vessel handling system useful for combinatorial chemistry

摘要

A system for holding laboratory or reaction vessels useful for performing combinatorial chemistry, particularly parallel array synthesis. The system includes a holder having O-ring lined apertures which retain reaction vessels inserted therein. The vessels each have an internal filter dividing the vessel interior volume into first and second chambers that are sealed and unsealed with separately operable caps. The system also includes a collection rack having vessel guides adapted to accommodate collection vessels used to collect materials within the reaction vessels. The vessel guides are arranged on the collection rack in the same pattern as the apertures are arranged on the holder such that the vessel guides align with the holder apertures when the collection rack and the holder are positioned in a stacked relationship. The system also includes a drain tray for convenient emptying of reaction vessels retained on the holder, and a machine for rotating the holder to rotate vessels retained on the holder.