1-HYDROXY-2-NAPHTHALINECARBOXYLATE SALT OF 4-HYDROXY-<EMI ID=0.191 HE=3 WI=3 TI=CHI>- [6-(4-PHENYLBUTOXY)HEXYL)AMINO) METHYL]-1,3-BENZENE DIMETHANOL IN FORM OF SPHERICAL CONGLOMERATIONS OF MICROCRYSTALS, METHOD OF SUPER THIN GRINDING, AND METHOD OF PREPARATION THEREOF

摘要

FIELD: chemical industry. SUBSTANCE: present invention describes 1-hydroxy-2- naphthaline carboxylate salt of 4-hydroxy-<EMI ID=0.192 HE=3 WI=3 TI=CHI>-[6-(4- phenylbutoxy)hexyl] amino) methyl)-1,3-benzenedimethanol in form of spherical coagulations of microcrystals. The letter are free flowing crumalle and finally ground and have preferably average particle size of 70-300 mm and average surface area of 4-12 <EMI ID=0.193 HE=3 WI=3 TI=CHI>. The present invention also describes preparation method which comprises cooling rapidly hot organic or aqueous salt solution with cold organic or aqueous organic solvent. EFFECT: improved properties of the title compounds. 25 cl, 2 dwg