发明名称 |
METHOD AND KIT FOR DIAGNOSIS OF AN INCREASED RISK OF CARDIOVASCULAR DISEASES |
摘要 |
The invention relates to a method for indicating groups at risk of cardiovascular diseases. In particular, the invention offers the possibility of determining whether a person, by smoking, has an increased risk of cardiovascular disease on the basis of a genetic predisposition. A polymorphism has now been found which is clearly associated with an increased risk of cardiovascular disease in smokers in contrast to non-smokers. Smokers who possess a specific allele are at appreciably greater risk than smokers who do not possess this allele. |
申请公布号 |
WO9831832(A1) |
申请公布日期 |
1998.07.23 |
申请号 |
WO1998NL00029 |
申请日期 |
1998.01.19 |
申请人 |
NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO;GROBBEE, DIEDERICK, EGBERTUS;KLUFT, CORNELIS |
发明人 |
GROBBEE, DIEDERICK, EGBERTUS;KLUFT, CORNELIS |
分类号 |
C12N15/09;A61B10/00;C12Q1/68;(IPC1-7):C12Q1/68;G01N33/50 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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