| 摘要 |
This invention relates to cardiac diseases improving agents substantially free from antagonistic action to type 1 receptor of angiotensin @ which participates to hypotensive action. Particularly, this invention relates to cardiac diseases improving agents composed of effective ingredients of aromatic compounds or pharmacologically acceptable salts thereof shown by below mentioned general formula. <CHEM> (wherein, substituents thereof typically include, R<1>, R<4>, R<13> representing hydrogen atom, an alkyl group, a haloalkyl group and so forth, R<8> representing -CO-, -SO2- or single bond, R<2> representing a 3-7 membered aliphatic cyclic amino group having at least one nitrogen atom, R<7> representing -CO- or -SO2-, and R<12> representing N-substituted valeramido group.) |
