USE OF Δ5 ANDROSTENES IN THE TREATMENT OF HIV WASTING SYNDROME

摘要

HIV-related weight loss, HIV-related cachexia and HIV-related wasting syndrome can be treated by administering therapeutic amounts of the steroid Δ5-androstene-3β-ol-7,17 dione and metabolizable precursors thereof, such as Δ5-androstene-3β-acetoxy-7,17 dione, which are readily metabolized in vivo to Δ5-androstene-3β-ol-7,17 dione. Such treatment can be prophylactic, modulatory, ameliorative or curative in nature.