NEPHROTROPIC DRUGS

摘要

Nephrotropic drugs and drug carriers delivering drugs carried thereon specifically to the kidney with the use of partial structures specifically recognized in the kidney. Since partial structures represented by the general formula (I): A-U-V- are nephrotropic, objective drugs can be obtained by introducing molecules with these structures into drugs. Compounds having such a partial structure together with another partial structure enabling the carriage of drugs are usable as carriers capable of delivering the drugs carried thereon specifically to the kidney. In said formula, A represents glycosyl such as glucosyl, mannosyl or 2-deoxyglucosyl: U represents O, S or NH; and V represents an aromatic hydrocarbon group or a linear or branched aliphatic C1-18 hydrocarbon group.