摘要 |
The invention relates to a matrix material provided with a number of bio-active materials, in particular drugs, comprising a substrate, polyethyleneimine (PEI) coupled to the substrate, and several bio-active materials adhering to the polyethyleneimine and/or substrate. The matrix material can be obtained by the following steps: (a) preparing, if necessary, the substrate for the introduction of coupling groups; (b) effecting contact between the substrate and a solution of PEI, if required in the presence of a carbodiimide; and (c) subsequently effecting contact between the substrate treated with PEI and one or more solutions of bio-active materials, if required in the presence of a |