| 发明名称 |
Proteaz engelleyicileri. |
| 摘要 |
Bu bulus cathepsin K dahil olmak üzere proteazlari, bu gibi bilesimlerin farmasötik terkiplerin ve osteoporoz dahil olmak üzere asiri kemik kaybi veya kikirdak veya matris bozulmasi, dis eti rahatsizligi ve periodontoz gibi dis eti hastaliklari; artrit, özellikle osteo artrit; paget hastaligi; habis hiperkalsemi; ve metabolik kemik hastaligi gibi hastaliklarin tedavisi için, bahsi geçen kemik kaybi veya asiri kikirdak veya matris bozulmasinin ihtiyaci olan hastaya bu bulusun bir bilesiminin verilmesi yoluyla önlenmesini içeren yöntemler saglamaktadir.
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| 申请公布号 |
TR9800767(T2) |
申请公布日期 |
1998.07.21 |
| 申请号 |
TR19980000767T |
申请日期 |
1996.10.30 |
| 申请人 |
SMITHKLINE BEECHAM CORPORATION |
发明人 |
THOMAS JOSEPH CARP;RENEE LOUISE DESJARLAIS;TIMOTHY FRANCIS GALLAGHER;STACIE MARIE HALBERT;HYE-JA OH;SCOTT KEVIN THOMPSON;DANIEL FRANK VEBER;DENNIS SHINJI YAMASHITA;JACK HWEKWO YEN |
| 分类号 |
A61K31/00;A61K31/16;A61K31/18;A61K31/34;A61K31/343;A61K31/38;A61K31/381;A61K31/41;A61K31/415;A61K31/4155;A61K31/4164;A61K31/4245;A61K31/425;A61K31/426;A61K31/427;A61K31/433;A61K31/44;A61K31/4427;A61K31/443;A61K31/4439;A61K31/445;A61K31/4465;A61K31/4523;A61K31/4525;A61K31/47;A61K31/4709;A61K31/495;A61K31/496;A61K31/4965;A61K31/497;A61K31/535;A61K31/5375;A61K31/5377;A61K31/54;A61K38/00;A61P1/00;A61P1/02;A61P19/00;A61P19/10;A61P29/00;A61P43/00;C07C235/50;C07C243/34;C07C271/22;C07C281/06;C07C311/16;C07C311/29;C07D211/62;C07D213/30;C07D213/71;C07D213/81;C07D215/36;C07D231/18;C07D233/56;C07D241/24;C07D249/10;C07D271/06;C07D271/10;C07D277/20;C07D277/36;C07D277/40;C07D277/56;C07D285/06;C07D285/12;C07D285/125;C07D285/135;C07D295/155;C07D295/20;C07D295/215;C07D307/91;C07D333/34;C07D333/76;C07D401/12;C07D405/12;C07D417/12;C07D417/14;C07K5/062;C07K5/083;C12N9/64;C12Q1/37;G01N33/573;(IPC1-7):C07D277/56 |
主分类号 |
A61K31/00 |
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