发明名称 |
Method for identifying and quantifying nucleic acid sequence aberrations |
摘要 |
A method for detecting nucleic acid sequence aberrations by detecting nucleic acid sequences having both a first and a second nucleic acid sequence type, the presence of the first and second sequence type on the same nucleic acid sequence indicating the presence of a nucleic acid sequence aberration. The method uses a first hybridization probe which includes a nucleic acid sequence that is complementary to a first sequence type and a first complexing agent capable of attaching to a second complexing agent and a second hybridization probe which includes a nucleic acid sequence that selectively hybridizes to the second nucleic acid sequence type over the first sequence type and includes a detectable marker for detecting the second hybridization probe.
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申请公布号 |
US5783387(A) |
申请公布日期 |
1998.07.21 |
申请号 |
US19950384497 |
申请日期 |
1995.02.06 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
LUCAS, JOE N.;STRAUME, TORE;BOGEN, KENNETH T. |
分类号 |
C12Q1/68;(IPC1-7):C12Q1/68;C07H21/02;C07H21/04;C12N15/00 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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