发明名称 |
POLYPEPTIDE SHOWING CARMINOMYCIN-4-O-METHYLTRANSFERASE ACTIVITY AND A METHOD OF ITS PREPARING |
摘要 |
FIELD: molecular biology, genetic engineering, biochemistry. SUBSTANCE: invention relates to polypeptide of molecular mass 38 700 Da showing activity of carminomycin-4-O-methyltransferase. Polypeptide is obtained by culturing strain-producers Escherichia coli or Streptomyces. Strains are transformed with recombinant plasmids pNHM 901 or pWHM 902 or pWHM 903 that contain DNA fragment of the identified nucleotide sequence. EFFECT: improved method of polypeptide preparing. 3 cl, 7 dwgi |
申请公布号 |
RU2115731(C1) |
申请公布日期 |
1998.07.20 |
申请号 |
RU19930054774 |
申请日期 |
1992.11.17 |
申请人 |
FARMATSIJA EHND APDZHON, S.P.A.;CHARL'Z RICHARD KHATCHINSON |
发明人 |
CHARL'Z RICHARD KHATCHINSON;KRISHNA MARTI MADDURI;FRANCHESKA TORTI;ANNA LUIZA KOLOMBO |
分类号 |
C12N9/10;C12N15/54;C12P19/56;C12R1/19;C12R1/465 |
主分类号 |
C12N9/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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