发明名称 Chemical synthesis of nucleosides analogs and their incorporation into polynucleotides
摘要 Novel nucleosides, process for chemical synthesis of nucleosides and incorporation of the nucleosides into polynucleotides are disclosed. Also described are polynucleotides, such as antisense, TFO and nucleic acid catalysts with one or more modifications, such as 2'-O-amino, L-nucleotides and the others.
申请公布号 AU5720498(A) 申请公布日期 1998.07.17
申请号 AU19980057204 申请日期 1997.12.19
申请人 RIBOZYME PHARMACEUTICALS, INC. 发明人 ALEXANDER KARPEISKY;LEONID BEIGELMAN;JASENKA MATULIC-ADAMIC
分类号 C12N9/22;A61K31/7056;A61K31/706;A61K31/7068;A61K31/7072;A61K31/7076;A61K31/708;A61K31/7115;A61P31/12;A61P35/00;C07H19/04;C07H19/048;C07H19/052;C07H19/06;C07H19/067;C07H19/10;C07H19/16;C07H19/167;C07H21/00;C07H21/02;C07K14/08;C12N5/10;C12N15/113;C12N15/85;C12N15/86;C12Q1/70 主分类号 C12N9/22
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