发明名称 |
Recombinant n-smases and nucleic acids encoding same |
摘要 |
Isolated nucleic acids are provided that encode human neutral sphingomyelinase (N-SMase) and N-SMase fragments and derivatives capable of hybridizing to such N-SMase-encoding nucleic acids. The invention also includes isolated recombinant human neutral sphingomyelinase (N-SMase) and N-SMase fragments and derivatives are also provided. Novel assays are also provided to identify compounds useful in the diagnosis or treatment of human neutral sphingomyelinase related disorders. |
申请公布号 |
AU5809398(A) |
申请公布日期 |
1998.07.17 |
申请号 |
AU19980058093 |
申请日期 |
1997.12.23 |
申请人 |
THE JOHNS-HOPKINS UNIVERSITY |
发明人 |
SUBROTO CHATTERJEE |
分类号 |
C12N15/09;A01N1/02;A61K38/00;A61K38/46;A61K39/395;A61P3/00;A61P29/00;A61P35/00;A61P43/00;C12N1/21;C12N9/16;C12Q1/34;C12Q1/68 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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