Vegf-b/receptor complex and uses thereof

摘要

Disclosed are complexes of Vascular Endothelial Growth Factor-B (VEGF-B) and the Flt-1 tyrosine kinase receptor; the use of such VEGF-B/Flt-1 complexes in assays for VEGF-B or for VEGF-B analogs characterized as having substantially the same binding affinity for a cell surface receptor as VEGF-B, and/or in promoting or antagonizing a VEGF-B-mediated cell response; and specific binding partners, e.g. antibodies, for such VEGF-B/Flt-1 complexes.