| 摘要 |
<p>Influenza virus-infected cells secrete α-N-acetylgalactosaminidase into blood stream, resulting in deglycosylation of Gc protein. This inactivates the MAF precursor activity of Gc protein, leading to immunosuppression. Thus, α-N-acetylgalactosaminidase activity in patient bloodstream can serve as diagnostic and prognostic index. Antibody-sandwich ELISA method and kits for influenza virus specific α-N-acetylgalactosaminidase as an antigen were developed to detect serum or plasma α-N-acetylgalactosa minidase activity in influenza patients and used as a diagnostic/prognostic index.</p> |
