ENZYMATIC PROCESSES FOR THE PREPARATION OF (S)-CYANOHYDRINS

摘要

The invention concerns an enantioselective process for preparing the (S)enantiomer of an optically active cyanohydrin by reacting an aldehyde or ketone with a cyanide group donor. According to this process, the aldehyde or ketone is reacted with a cyanide group donor in an organic diluent in the presence of a recombinant (S)-hydroxynitrile lyase from Hevea brasiliensis, the resultant (S)-cyanohydrin being isolated from the reaction mixture.