Compounds and methods for inactivating pathogens in materials are described, including compositions and methods for inactivating pathogens in biological materials such as red blood cell preparations and plasma. The compounds and methods may be used to treat materials intended for in vitro or in vivo use, such as clinical testing or transfusion. The compounds are designed to specifically bind to and react with nucleic acid, and then to degrade to form breakdown products. The degradation reaction is preferably slower than the reaction with nucleic acid.
申请公布号
WO9830545(A1)
申请公布日期
1998.07.16
申请号
WO1998US00532
申请日期
1998.01.06
申请人
CERUS CORPORATION;COOK, DAVID;MERRITT, JOHN;NERIO, AILEEN;RAPOPORT, HENRY;STASSINOPOULOS, ADONIS;WOLLOWITZ, SUSAN;MATEJOVIC, JON
发明人
COOK, DAVID;MERRITT, JOHN;NERIO, AILEEN;RAPOPORT, HENRY;STASSINOPOULOS, ADONIS;WOLLOWITZ, SUSAN;MATEJOVIC, JON