Specific antagonists for prokaryotic or eukaryotic integral membrane proteins are provided. The antagonists are peptides having the amino acid sequence of a transmembrane domain of the integral membrane proteins or of a portion of analogue thereof. Methods are provided for preventing or treating disorders characterised by disordered function of an integral membrane protein by administration of a specific peptide antagonist of the integral membrane protein.
申请公布号
WO9735881(A3)
申请公布日期
1998.07.16
申请号
WO1997CA00203
申请日期
1997.03.26
申请人
NG, GORDON, Y., K.;SEEMAN, PHILIP;GEORGE, SUSAN, R.;O'DOWD, BRIAN, F.
发明人
NG, GODRON, Y., K.;SEEMAN, PHILIP;GEORGE, SUSAN, R.;O'DOWD, BRIAN, F.