COMBINATION THERAPY USING A TNF BINDING PROTEIN FOR TREATING TNF-MEDIATED DISEASES
摘要
The invention relates to methods for treating or preventing acute and/or chronic arthritis. The method comprises administering to patients in need thereof therapeutically effective amounts of a TNF binding protein and methotrexate (N-[4-[[2,4-diamino-6-pteridinyl)methylamino]benzoyl]-L-glutamic acid). In a preferred embodiment, the TNF binding protein is sTNFR-I or sTNFR-II. The invention also relates to pharmaceutical compositions containing a TNF binding protein and methotrexate useful in such methods. 00000
申请公布号
WO9824463(A3)
申请公布日期
1998.07.16
申请号
WO1997US22733
申请日期
1997.12.08
申请人
AMGEN INC.;BENDELE, ALISON, M.;SENNELLO, REGINA, M.;EDWARDS, CARL, K.
发明人
BENDELE, ALISON, M.;SENNELLO, REGINA, M.;EDWARDS, CARL, K.