| 摘要 |
<p>A process for producing cysteine derivatives having especially high optical purities economically advantageously at a high production efficiency even on an industrial scale. The process for producing cysteine derivatives represented by general formula (III) (wherein R0 represents hydrogen or an amino-protecting group like R1; R1 represents an amino-protecting group; R2 represents a carboxyl-protecting group; and R3 represents C¿1-7? alkyl, C6-10 aryl, or C7-10 aralkyl) is one which comprises reacting an amino acid derivative represented by general formula (I) (wherein R?1, R0, and R2¿ are each as defined above; and X represents a leaving group) with a thiol compound represented by general formula (II) (wherein R3 is as defined above), wherein the reaction is conducted in an organic raction medium in the presence of a base and water.</p> |
