| 发明名称 |
BIOCONJUGATION OF MACROMOLECULES |
| 摘要 |
This invention discloses a novel method for conjugating macromolecules to other molecular entities. Specifically, this invention discloses a method for conjugating or derivatizing macromolecules, such as oligonucleotides and proteins, using cycloaddition reactions, such as the Diels-Alder reaction or 1,3-dipolar cycloadditions. Included in the invention are the novel bioconjugated macromolecules that can be prepared according to the method of the invention.
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| 申请公布号 |
CA2277159(A1) |
申请公布日期 |
1998.07.16 |
| 申请号 |
CA19982277159 |
申请日期 |
1998.01.08 |
| 申请人 |
PROLIGO LLC |
发明人 |
STEPHENS, ANDREW;GOLD, LARRY;VAGLE, KURT;MCGEE, DANNY;EATON, BRUCE;HILL, KEN;PIEKEN, WOLFGANG |
| 分类号 |
C07H19/067;C07H19/04;C07H19/10;C07H19/20;C07H21/00;C07H21/02;C07H21/04;C08G65/329;C08G85/00;C12N15/09;C12N15/113;C12P19/34;C12Q1/68;(IPC1-7):C07H19/00;C10M107/00;C07C2/02;C07C2/50 |
主分类号 |
C07H19/067 |
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