发明名称 STRUCTURE FOR EXPRESSION OF p16 AND ITS APPLICATION WHEN TREATING CANCER
摘要 <p>A variety of genetic constructs are disclosed that will find both in vitro and in vivo use in the area of tumor biology and cancer therapy. In particular, expression constructs are provided that contain a p16 encoding region and other regulatory elements necessary for the expression of a p16 transcript. One version of the expression construct is a replication-deficient adenoviral vector. Also provided are methods for the transformation of cell lines and the inhibition of cancer cell proliferation.</p>
申请公布号 CZ9800154(A3) 申请公布日期 1998.07.15
申请号 CZ19980000154 申请日期 1996.07.17
申请人 BOARD OF REGENTS 发明人 JIN XIAOMEI;ROTH JACK
分类号 C12N15/09;A61K38/00;A61K48/00;A61P35/00;C07K14/47;C12N5/10;C12N15/00;C12Q1/68;C12R1/92;(IPC1-7):C12N15/86;C12N15/79;C12N15/65 主分类号 C12N15/09
代理机构 代理人
主权项
地址