| 摘要 |
PCT No. PCT/EP97/07307 Sec. 371 Date Jul. 14, 1999 Sec. 102(e) Date Jul. 14, 1999 PCT Filed Dec. 29, 1997 PCT Pub. No. WO98/31704 PCT Pub. Date Jul. 23, 1998Compounds of formula (I) wherein X is -CH2-, -CO- or direct linkage, Y is -O-, -S- or -NH-, R1 is phenyl, R2=H or phenyl and R3 is H or -CH3- and their pharmaceutically acceptable salts have tachykinin antagonist activity and are useful as pharmaceuticals e.g. for the treatment of pain and migraine. |
