| 摘要 |
A process is provided for coupled microbial saccharide fermentation and esterification to produce an esterified fermentation product from a saccharide. A microorganism capable of fermenting a saccharide to produce a water-soluble organic acid, alcohol or acetylcoenzyme A, and capable of producing an esterase or alcohol acetyltransferase is attached to a hydrophilic carrier to immobilize the microorganism. The immobilized microorganism is contacted with a hydrophobic organic solvent having dissolved therein a water-insoluble alcohol, organic acid or aldehyde. The organic solvent at an interface is in contact with an aqueous medium containing a saccharide. The microorganism is grown at the interface to ferment the saccharide and produce a water-soluble organic acid, alcohol or acetylcoenzyme A. The esterase or alcohol acetyltransferase produced by the microorganism causes the water-soluble organic acid, alcohol or acetylcoenzyme A to undergo an esterification reaction with the water-insoluble alcohol or organic acid in the organic solvent or with a water-insoluble organic acid produced by microbial oxidation of the water-insoluble alcohol in the organic solvent or with a water-insoluble alcohol or organic acid produced by microbial oxidation of the water-insoluble aldehyde in the organic solvent to a produce an esterified fermentation product from the saccharide.
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