| 摘要 |
Antisense oligomers of the formula <IMAGE> I wherein R1, R2 and R4 are independently hydrogen, lower alkyl or acyl; R3 is hydrogen or lower alkyl; B is a nucleobase or a protected nucleobase, such that said oligomer has a sequence of bases complementary to a selected RNA; n is 5 to 30; X is NR3R4; Y is OR3, or NHR3; as well as, pharmaceutically acceptable salts thereof.
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