发明名称 FLUOROALKOXYBENZYLAMINE DERIVATIVES OF NITROGEN-CONTAINING HETEROCYCLES, PHARMACEUTICAL COMPOSITION, METHOD OF INHIBITION OF SUBSTANCE P EFFECT IN MAMMALIAN
摘要 FIELD: organic chemistry. SUBSTANCE: invention relates to new fluoroalkoxybenzylamine derivatives of nitrogen-containing heterocyclic compounds, in part, compounds of the formula (I) <EMI ID=0.69 HE=18 WI=33 TI=CHI> where Q, X<SP>1</SP>,X and X have values indicated above. These new compounds are used for treatment of patients with inflammatory disease, disorders of central nervous system and other damages. EFFECT: improved method of synthesis of new compounds indicated above. 26 ex, 1 tbl, 31 cld
申请公布号 RU2114848(C1) 申请公布日期 1998.07.10
申请号 RU19930058531 申请日期 1992.05.05
申请人 PFAJZER INK. 发明人 DZHON ADAMS LOU III;TERRI DZHEHJ ROUZEN
分类号 A61K31/445;A61K31/435;A61K31/439;A61K31/451;A61K31/47;A61K31/473;A61K31/55;A61P25/00;A61P25/18;A61P25/20;A61P25/24;A61P25/26;A61P29/00;A61P37/08;C07C45/44;C07C45/51;C07C45/67;C07C45/71;C07C47/55;C07C47/575;C07D207/14;C07D209/52;C07D211/56;C07D211/76;C07D215/42;C07D221/04;C07D453/00;C07D453/02;C07D471/08;C07D471/18;C07D487/08;C07D498/18;C07D513/18;(IPC1-7):C07D487/08 主分类号 A61K31/445
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